
A newly published 24-week, randomized, double-blind, placebo-controlled clinical study evaluated CaloCurb Clinical in overweight and obese adults participating in a lifestyle modification program. Researchers found that participants taking CaloCurb Clinical experienced meaningful reductions in body weight, body fat, and visceral fat while maintaining muscle mass throughout the study.
As you all know, loss of lean muscle mass with weight loss drugs (especially GLP-1 RAs) is one of the biggest criticisms of the medication- well, in this 24-week study of overweight and obese adults using Calocurb CLINICAL 250mg twice daily resulted in:
- -3.77kg (8.29lb) weight loss
- -4.33% body weight
- -4.49kg (9.87lb) fat loss
- -32.5cm2 visceral fat loss
- +0.92kg muscle mass gain
Some things to note about the attached graphics below:
- This is a Long-term study showing statistically significant weight loss with minimal lifestyle counseling
- Hunger and cravings typically RISE during weight loss studies but here, we see that Calocurb CLINICAL kept hunger and cravings significantly suppressed!
- Fat loss was GREATER than weight loss and muscle mass was maintained – instead of the typical muscle mass loss there was a slight gain of muscle mass AND fat loss was greater than the weight loss due to this gain in muscle mass.
Hunger Suppression:
Craving Suppression:
In summary, Calocurb Clinical is the most potent botanical bitter compound in the world, and that preliminary data resulted in an 18% decrease in caloric intake. Now we have real world weight loss data.
The initial challenges with Calocurb have been GI-related symptoms at initiation of Calocurb dosing. This is a tolerance issue and not a safety issue. For some patients, initiating Calocurb without a proper titration strategy can lead to GI discomfort and loose stool. Being proactive and confident in educating patients on how to successfully onboard Calocurb can reduce risk for some of these effects.
Recommended Onboarding Approach
Take every capsule with a full glass of water at least 1 hour prior to meals.
· 1 – 125mg capsule daily until GI symptoms are resolved.
· 1 – 125mg capsule twice daily until GI symptoms are resolved.
· 2 – 125mg capsules daily until GI symptoms are resolved.
· 2 – 125mg capsules twice daily until GI symptoms are resolved.
· Then graduate to 1- 250mg delayed release caps 1x/day
· Then eventually 1 – 250mg delayed release cap BID
Calocurb has a 4–6-hour half-life. What clinics have been doing that have been using Calocurb is telling their patients to set up a reminder in their phones 4-5 hours after the first dose of the day. It’s not critical that they eat within 1 hour but taken at least 1 hour prior to a meal. This helps the patients remain compliant and preventing your patients from forgetting to take the 2nd dose when they are sitting down to eat.
Here is a video so that shows are how and when to take.

In closing, Calocurb is the most effective and scientifically proven weight loss nutraceutical. With the proper on boarding of patients and the increased benefits compared to the GLP-1 agonists, Calocurb can become a safe, effective product for patients that need a weight loss maintenance plan and/or a weight loss tool if they are not candidates for the injections and or oral versions that come with a list of unwanted risks.
Calocurb Clinical is not allowed to be sold online.
Please stop in or call us 781-893-3870 x3 to order